Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course.
Herman T den DekkerKimberley BurrowsJanine F FelixLucas A SalasIvana ProkicJin YaoSheryl L Rifas-ShimanCarlos Ruiz-ArenasN AminMariona BustamanteDawn L DeMeoA John HendersonCaitlin G HoweMarie-France HivertM Arfan IkramJohan C de JongsteLies LahoussePooja R MandaviyaJoyce B van MeursMariona PinartGemma C SharpLisette StolkAndré G UitterlindenJosep M AntoAugusto A LitonjuaCarrie V BretonGuy G BrusselleJordi SunyerGeorge Davey SmithCaroline L ReltonVincent W V JaddoeLiesbeth DuijtsPublished in: The European respiratory journal (2019)
Our findings suggest that the epigenetic status of the newborn affects respiratory health and disease across the life course.