Melting curve analysis reveals false-positive norovirus detection in a molecular syndromic panel.
Nancy MaticTanya LawsonMatthew YoungWillson JangJennifer BilawkaLeah GowlandGordon RitchieVictor LeungMichael PayneAleksandra StefanovicMarc G RomneyChristopher F LowePublished in: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (2024)
Although not described in the manufacturer's Instructions for Use, we propose routine manual review of melting curves for the BioFire GI panel prior to reporting, to mitigate potential false-positive norovirus results.