Comparison of Two-Bag Versus Three-Bag N-Acetylcysteine Regimens for Pediatric Acetaminophen Toxicity.

Sindhu SudanaguntaAlexa Camarena-MichelStephanie PenningtonJan LeonardChristopher HoyteGeorge Sam Wang

Published in: The Annals of pharmacotherapy (2022)

A significant decrease in cutaneous NAARs and MEs was observed in pediatric patients by combining the first two bags of the traditional three-bag NAC regimen. In pediatric populations, a two-bag NAC regimen for acetaminophen overdose may improve medication tolerance and safety.

Keyphrases

transcription factor
liver injury
drug induced
emergency department
genome wide analysis