Incomplete ART adherence is associated with higher inflammation in individuals who achieved virologic suppression in the START study.

Jose R Castillo-Mancilla Andrew N PhillipsJames D NeatonJacqueline NeuhausShweta SharmaJason V BakerSimon CollinsSharon MannheimerSarah PettVeronique Touzeau-RömerMark N PolizzottoJens D LundgrenEdward M Gardnernull null

Published in: Journal of the International AIDS Society (2020)

Incomplete ART adherence was associated with higher IL-6 levels in individuals who achieved virologic suppression early after ART initiation in START. A potential similar association for SAA requires confirmation. These findings suggest a role for identifying strategies to maximize ART adherence even during virologic suppression. ClinicalTrials.gov number: NCT00867048.

Keyphrases

hiv infected
antiretroviral therapy
oxidative stress
glycemic control
risk assessment
adipose tissue
human health