Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion.
Jennifer L ChiemIskra IvanovaAndrew ParkerWalter KrengelNathalia JimenezPublished in: Paediatric anaesthesia (2017)
Tranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72-year-old man. We report a case of a delayed anaphylactic reaction in a pediatric patient undergoing posterior spine fusion; and discuss the intraoperative management of the acute event, immunologic confirmation, and subsequent anesthetic approach.
Keyphrases
- minimally invasive
- liver failure
- young adults
- coronary artery bypass
- mental health
- spinal cord
- respiratory failure
- drug induced
- patients undergoing
- aortic dissection
- childhood cancer
- chemotherapy induced
- surgical site infection
- hepatitis b virus
- intensive care unit
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome