A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus.
Kensuke SuzukiKazunori NagasakaKatsutoshi OdaHiroyuki AbeDaichi MaedaYoko MatsumotoTakahide ArimotoKei KawanaMasashi FukayamaYutaka OsugaTomoyuki FujiiPublished in: BMC cancer (2016)
This is the first reported case of comorbid endometrial cancer, SLE, and aggressive LAM metastasizing to regional lymph nodes, and strengthens the clinical evidence for a common role of mTOR pathway hyperactivity and estrogen responsiveness in the pathophysiology of metastasizing lesions of the genital tract.