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A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus.

Kensuke SuzukiKazunori NagasakaKatsutoshi OdaHiroyuki AbeDaichi MaedaYoko MatsumotoTakahide ArimotoKei KawanaMasashi FukayamaYutaka OsugaTomoyuki Fujii
Published in: BMC cancer (2016)
This is the first reported case of comorbid endometrial cancer, SLE, and aggressive LAM metastasizing to regional lymph nodes, and strengthens the clinical evidence for a common role of mTOR pathway hyperactivity and estrogen responsiveness in the pathophysiology of metastasizing lesions of the genital tract.
Keyphrases
  • endometrial cancer
  • systemic lupus erythematosus
  • lymph node
  • disease activity
  • cell proliferation
  • early onset
  • estrogen receptor
  • rheumatoid arthritis
  • neoadjuvant chemotherapy
  • sentinel lymph node