Testing for N-methyl-d-aspartate Receptor Autoantibodies in Clinical Practice.

John BrooksMelanie L YarbroughRobert C BucelliGregory S Day

Published in: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (2019)

Commercial kits may yield lower-than-expected rates of NMDAR IgG autoantibody detection in serum when run in exemplar clinical (nonreference) laboratories. Additional studies are needed to decipher the factors that contribute to lower-than-expected rates of serum positivity. CSF testing is recommended in patients with suspected anti-NMDAR encephalitis.

Keyphrases

clinical practice
systemic lupus erythematosus
case control
real time pcr
cerebrospinal fluid
sensitive detection