Role of New Anatomy, Biliopancreatic Reflux, and Helicobacter Pylori Status in Postgastrectomy Stump Cancer.
Luigi BassoGaetano GalloDaniele BiacchiMaria Vittoria CaratiGiuseppe CavallaroLuca EspositoAndrea GiulianiLuciano IzzoPaolo IzzoAntonietta LamazzaAndrea PolistenaMariarita TaralloAlessandro MicarelliEnrico FioriPublished in: Journal of clinical medicine (2022)
Distal gastrectomy for benign gastroduodenal peptic disease has become rare, but it still represents a widely adopted procedure for advanced and, in some countries, even for early distal gastric cancer. Survival rates following surgery for gastric malignancy are constantly improving, hence the residual mucosa of the gastric stump is exposed for a prolonged period to biliopancreatic reflux and, possibly, to Helicobacter pylori (HP) infection. Biliopancreatic reflux and HP infection are considered responsible for gastritis and metachronous carcinoma in the gastric stump after oncologic surgery. For gastrectomy patients, in addition to eradication treatment for cases that are already HP positive, endoscopic surveillance should also be recommended, for prompt surveillance and detection in the residual mucosa of any metaplastic-atrophic-dysplastic features following surgery.
Keyphrases
- helicobacter pylori
- minimally invasive
- helicobacter pylori infection
- coronary artery bypass
- roux en y gastric bypass
- robot assisted
- public health
- end stage renal disease
- gastric bypass
- surgical site infection
- ejection fraction
- prostate cancer
- squamous cell carcinoma
- chronic kidney disease
- peritoneal dialysis
- percutaneous coronary intervention
- patient reported outcomes
- papillary thyroid
- ultrasound guided
- obese patients
- lymph node metastasis
- sensitive detection
- free survival