Co-culture of Platelets with Monocytes Induced M2 Macrophage Polarization and Formation of Foam Cells: Shedding Light on the Crucial Role of Platelets in Monocyte Differentiation

Mahdieh Mehrpouri Soroush Sadeghi Mohammad Hossien Mohammadi Mohammad Esmail Gheydari Esmaeil Shahabi Satlsar Mohsen Hamidpour

Published in: Turkish journal of haematology : official journal of Turkish Society of Haematology (2019)

Our results indicate that platelets from CAD patients could provoke monocyte differentiation into macrophages with an M2 phenotype, which in turn may participate in an atheroprotective process.

Keyphrases

dendritic cells
end stage renal disease
peripheral blood
ejection fraction
newly diagnosed
induced apoptosis
peritoneal dialysis
immune response
patient reported outcomes
drug induced
living cells
patient reported
single molecule