Phenotypic variability in ALS-FTD and effect on survival.
Rebekah M AhmedEmma M DevenneyCherie Strikwerda-BrownJohn R HodgesOlivier PiguetMatthew C KiernanPublished in: Neurology (2020)
Initial motor presentation in ALS-FTD leads to faster progression than in those with a cognitive presentation, despite similar overall cognitive deficits. These findings suggest that disease progression in ALS-FTD may be critically linked to physiologic and motor changes.