Improvement of Adipose Macrophage Polarization in High Fat Diet-Induced Obese GHSR Knockout Mice.

Fang YuanJian MaXinxin XiangHe LanYanhui XuJing ZhaoYin LiWeizhen Zhang

Published in: BioMed research international (2018)

The GHSR-/- mice fed with HFD showed suppressed adipose inflammation, reduced macrophage infiltration, and enhanced M2 polarization of macrophages in adipose tissue, which improved insulin sensitivity.

Keyphrases

high fat diet induced
adipose tissue
insulin resistance
high fat diet
oxidative stress
metabolic syndrome
skeletal muscle
bariatric surgery