Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies.

Sigrid P DuboisMilos D MiljkovicThomas A FleisherStefania PittalugaJennifer Hsu-AlbertBonita R BryantMichael N PetrusLiyanage P PereraJürgen R MüllerJoanna H ShihThomas A Waldmann Kevin C Conlon

Published in: Journal for immunotherapy of cancer (2021)

NCT01572493, NCT03759184, NCT03905135, NCT04185220 and NCT02689453.

Keyphrases

combination therapy
nk cells
low dose