Relapse Risk and Safety of Long-Term Tocilizumab Use Among Patients With Giant Cell Arteritis: A Single-Enterprise Cohort Study.
Matthew J SamecJigisha RakholiyaHannah LangenfeldCynthia S CrowsonAndy AbrilBenjamin WangLester MertzAlicia Rodriguez-PlaPankaj BansalMichelle BurkeJane JaquithCornelia M WeyandKenneth J WarringtonMatthew J KosterPublished in: The Journal of rheumatology (2023)
TCZ is well tolerated in GCA, with low rates of discontinuation for AESIs. However, relapse occurred in > 50% despite median treatment > 12 months. Since the duration of TCZ prior to discontinuation did not significantly affect subsequent risk of GCA recurrence, further research is needed to determine the optimal duration of therapy.