IDH1/MDH1 deacetylation promotes acute liver failure by regulating NETosis.

Yukun WangChunxia ShiJin GuoDanmei ZhangYanqiong ZhangLong ZhangZuo-Jiong Gong

Published in: Cellular & molecular biology letters (2024)

Deacetylation of IDH1 and MDH1 reduces their activity and promotes the formation of NETs. This change aggravates the progression of acute liver failure.

Keyphrases

liver failure
hepatitis b virus
low grade
wild type
drug induced