Therapy duration and improvement of ventricular function in de novo heart failure: the Heart Failure Optimization study.
Christian VeltmannDavid DunckerMichael DoeringSiva GummadiMichael RobertsonThomas WittlingerByron J ColleyChristian PeringsOrvar JonssonJohann BauersachsRobert SanchezLars Siegfried MaierPublished in: European heart journal (2024)
Continuous optimization of guideline-recommended medical therapy for at least 180 days in HFrEF is associated with additional LVEF improvement > 35%, allowing for better decision-making regarding preventive implantable cardioverter-defibrillator therapy.