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Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats.

Daisuke GotohKazumasa TorimotoHirotaka IwasakiTakashi IwamotoYosuke MorizawaShunta HoriMakito MiyakeNobumichi TanakaAkihide HirayamaEiichiro NishiKiyohide Fujimoto
Published in: Lower urinary tract symptoms (2019)
Tadalafil restored urethral relaxation function and detrusor responses to EFS and carbachol during the initial phase of diabetes.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • lower urinary tract symptoms
  • benign prostatic hyperplasia
  • botulinum toxin
  • adipose tissue
  • single molecule
  • metabolic syndrome
  • urinary incontinence