TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma.
Rachel L CliffordChen Xi YangNick FishbaneJamie PatelJulia L MacIsaacLisa M McEwenSean T MayMarcos Castellanos-UribeParameswaran NairMa'en ObeidatMichael S KoborAlan J KnoxTillie-Louise HackettPublished in: Clinical epigenetics (2020)
Differential methylation of TWIST1 is a robust cell marker of airway and parenchymal lung fibroblasts. Airway and parenchymal fibroblast DNA methylation are differentially altered in individuals with asthma, and the role of both cell types should be considered in the pathogenesis of asthma.