Population pharmacokinetics of linezolid and its major metabolites PNU-142300 and PNU-142586 in adult patients.
Norihiro SakuraiHiroshi KawaguchiJunko AbeGaku KuwabaraWaki ImotoWataru ShibataKoichi YamadaHiroyuki YasuiYasutaka NakamuraHiroshi KakeyaPublished in: Pharmacotherapy (2022)
, and AUC appropriately. The model was found to be a potentially useful tool for future studies on optimal dosing and toxicity analysis.