CDC42-mediated Wnt signaling facilitates odontogenic differentiation of DPCs during tooth root elongation.

Tao ZhouGuoqing ChenYuchan XuShuning ZhangHuilin TangTao QiuWeihua Guo

Published in: Stem cell research & therapy (2023)

We innovatively revealed that CDC42 was responsible for guiding root elongation in a mesenchyme-specific manner. Furthermore, CDC42-mediated canonical Wnt signaling regulated odontogenic differentiation of DPCs during root formation.

Keyphrases

cell cycle
transcription factor
single cell