Genomic and Phylogenomic Characterization of Carbapenem-resistant Pseudomonas aeruginosa 'High-risk' Clone O4/ExoS+/ST654 Circulating in Chilean Hospitals.
Andrés Opazo-CapurroOmar Alejandro Aguilar-VeraPaulina González-MuñozLuis Amsteins-RomeroMonserrat QuirogaAntonia EncinaNéstor Herrera-ChávezMario Quezada-AguiluzAlejandro Aguayo-ReyesFelipe Morales-LeónVijna IllescaRodrigo VeraFabiola SalgadoPatricio SuazoLuz María FuenzalidaHelia Bello-ToledoSantiago Castillo-RamírezGerardo González-RochaPublished in: Journal of global antimicrobial resistance (2024)
Our report represents the most comprehensive phylogenomic study of a CRPA high-risk clone ST654 to date. Our analyses suggest that this lineage is undergoing a divergent evolutionary path in Chile, because most of the isolates were KPC producers and were O4 serotype, differing from previous descriptions, which underline the relevance of performing molecular surveillance on this pathogen.