Nodal positivity decreases with age in women with early-stage, hormone receptor-positive breast cancer.
Stephanie M Downs-CannerCharles E GaberRaphael J LouiePaula D StrassleKristalyn K GallagherHyman B MussDavid W OllilaPublished in: Cancer (2019)
Axillary surgery may be safely omitted for many older women with ER+, clinically node-negative, early-stage breast cancer. Nodal positivity declines with advancing age, and this suggests varied biology in older patients versus younger patients.
Keyphrases
- early stage
- lymph node
- positive breast cancer
- sentinel lymph node
- neoadjuvant chemotherapy
- end stage renal disease
- ejection fraction
- newly diagnosed
- minimally invasive
- chronic kidney disease
- peritoneal dialysis
- physical activity
- prognostic factors
- coronary artery bypass
- endoplasmic reticulum
- coronary artery disease
- young adults
- percutaneous coronary intervention
- locally advanced
- surgical site infection