USP15 Represses Hepatocellular Carcinoma Progression by Regulation of Pathways of Cell Proliferation and Cell Migration: A System Biology Analysis.

Yiyue RenZhen SongJens RieserJörg AckermannIna KochXingyu LvTong JiXiujun Cai

Published in: Cancers (2023)

USP15 may suppress tumorigenesis of HCC by regulating pathway clusters of signal transduction for gene expression, cell cycle, and DNA repair. For the first time, the tumorigenesis of HCC is studied from the viewpoint of the pathway cluster.

Keyphrases

cell cycle
dna repair
cell proliferation
cell migration
gene expression
dna damage
dna methylation
dna damage response
oxidative stress
solid state