Tryptophan-Kynurenine Pathway Activation and Cognition in Virally Suppressed Women With HIV.
Eran Frank ShorerRaha M DastgheybAudrey L FrenchElizabeth DaubertRalph MorackTsion YohannesClary ClishDeborah GustafsonAnjali SharmaAndre RogandoQibin QiHelen BurgessLeah H RubinKathleen M WeberPublished in: Journal of acquired immune deficiency syndromes (1999) (2024)
IDO activation (K:T) was associated with worse fine motor control in VS-WWH independent of measured systemic inflammation. Further studies investigating biological mechanisms linking IDO activation to fine motor function among VS-WWH are warranted.