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Estrogen receptor alpha (ESR1) gene polymorphism (rs2234693 and rs2046210) with breast cancer risk in pashtun population of Khyber Pakhtunkhwa.

Savera ShahzadNajeeb Ullah KhanWafa SombalRizwan Ullah ShahAakif Ullah KhanAqib IqbalIqbal Munir
Published in: Molecular biology reports (2023)
It is concluded that ESR1-rs2234693 is not associated with breast cancer, while rs2046210 is significantly associated with the risk of breast cancer in Khyber Pakhtunkhwa population. Further, to confirm the exact situation of ESR1 polymorphism, ESR1 existing and other SNPs need to be investigated in diverse data sets.
Keyphrases
  • estrogen receptor
  • breast cancer risk
  • genome wide
  • mass spectrometry
  • big data
  • gene expression
  • dna methylation
  • atomic force microscopy
  • data analysis
  • single molecule
  • high speed