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Assessment of anti-PD-(L)1 for patients with coexisting malignant tumor and tuberculosis classified by active, latent, and obsolete stage.

Shan SuMei-Feng YeXiao-Ting CaiXue BaiZhi-Hao HuangSi-Cong MaJian-Jun ZouYu-Xiang WenLi-Juan WuXue-Jun GuoXian-Lan ZhangWen-Chang CenDuo-Hua SuHui-Yi HuangZhong-Yi Dong
Published in: BMC medicine (2021)
This study demonstrated that patients with coexisting malignant tumor and tuberculosis benefited equally from anti-PD-(L)1 therapy, and anti-tuberculosis response was unimpaired for those with active tuberculosis. Notably, the combination of anti-PD-(L)1 and anti-tuberculosis therapy was well-tolerated without significant unexpected toxic effects.
Keyphrases
  • mycobacterium tuberculosis
  • pulmonary tuberculosis
  • hiv aids
  • stem cells
  • emergency department
  • adverse drug
  • antiretroviral therapy
  • smoking cessation
  • replacement therapy