Comparison of bivalirudin versus heparin in adult extracorporeal membrane oxygenation anticoagulant therapy: A retrospective case-control study.
Yaowei TongJulaiti RouzhahongWangtao ZhouRui WangYuqiang WangYucheng RenJu GuoYing LiZhengkai WangYunlin SongPublished in: The International journal of artificial organs (2023)
In V-V ECMO-supported adult patients, systemic anticoagulation with bivalirudin has achieved the same anticoagulation targets as heparin with less frequency of major bleeding events and lower requirement for blood products without significantly increased risk of thrombosis. Bivalirudin most likely is a safe and effective anticoagulation method for adult patients supported by V-V ECMO.
Keyphrases
- extracorporeal membrane oxygenation
- venous thromboembolism
- atrial fibrillation
- percutaneous coronary intervention
- acute respiratory distress syndrome
- respiratory failure
- pulmonary embolism
- mechanical ventilation
- acute coronary syndrome
- growth factor
- coronary artery disease
- stem cells
- childhood cancer
- clinical evaluation