Association between plasminogen activator inhibitor-1 and cardiovascular events: a systematic review and meta-analysis.

Richard G JungPouya MotazedianF Daniel RamirezTrevor SimardPietro Di SantoSarah VisintiniMohammad Ali FarazAlisha LabinazYoung JungBenjamin Hibbert

Published in: Thrombosis journal (2018)

Elevated plasma PAI-1 antigen levels are associated with MACE. Definitive studies are needed to ascertain if PAI-1 acts simply as a marker of risk or if it is indeed a bona fide therapeutic target.

Keyphrases

cardiovascular events
coronary artery disease
cardiovascular disease
case control
locally advanced
radiation therapy
breast cancer risk