Micro- and macrovascular cardiac allograft vasculopathy in relation to 91 cardiovascular biomarkers in heart transplant recipients-An exploratory study.
Kamilla Pernille BjerreTor Skibsted ClemmensenSteen Hvitfeldt PoulsenAnne-Mette HvasNiels Ramsing HolmErik Lerkevang GroveKirsten BoucheloucheSteen Dalby KristensenHans EiskjaerPublished in: Clinical transplantation (2020)
We identified consistent changes in two proteins involved in cholesterol homeostasis which may be important players in the pathogenesis of CAV: PON3 and PCSK9. NT-proBNP also showed consistent changes across all groups but only reached statistical significance in patients with microvascular CAV. Our results warrant further validation in future studies.