Gene Expression Profiling in Kidney Transplants with Immune Checkpoint Inhibitor-Associated Adverse Events.
Benjamin A AdamNaoka MurakamiGraeme ReidKatie DuRuqaya JasimChristie L BoilsLihong BuPeter D HillAllan G MurrayKarine RenaudinCandice A RoufosseAstrid WeinsKevin WenLeonardo V RiellaMichael MengelPublished in: Clinical journal of the American Society of Nephrology : CJASN (2021)
These results indicate that, although there is significant molecular similarity between immune checkpoint inhibitor-associated rejection and acute interstitial nephritis, biopsy-based measurement of IFI27 gene expression represents a potential biomarker for differentiating these entities.