Antimicrobial activity of antibiotics on biofilm formed by Staphylococcus aureus and Pseudomonas aeruginosa in an open microfluidic model mimicking the diabetic foot environment.
Cassandra PougetAlix PantelCatherine Dunyach-RemyChloé MagnanAlbert SottoJean-Philippe LavignePublished in: The Journal of antimicrobial chemotherapy (2023)
The combination of CWM and the BioFlux™ microfluidic system represents a valuable tool to screen the potential antimicrobial activity of antibiotics under conditions mimicking those encountered in DFI. It could help clinicians in their management of chronic wounds.
Keyphrases
- pseudomonas aeruginosa
- staphylococcus aureus
- high throughput
- biofilm formation
- circulating tumor cells
- single cell
- cystic fibrosis
- acinetobacter baumannii
- palliative care
- label free
- candida albicans
- methicillin resistant staphylococcus aureus
- escherichia coli
- risk assessment
- drug resistant
- climate change
- multidrug resistant