Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes.

Peixin DongYing XiongJunming YueDaozhi XuKei IhiraYosuke KonnoNoriko KobayashiYukiharu TodoHidemichi Watari

Published in: Journal of experimental & clinical cancer research : CR (2019)

NEAT1 initiates a miR-361-mediated network to drive aggressive EC progression. These data support a rationale for inhibiting NEAT1 signaling as a potential therapeutic strategy for overcoming aggressive EC progression and chemoresistance.

Keyphrases

long noncoding rna
endometrial cancer
cell proliferation
long non coding rna
clinical trial
transcription factor
signaling pathway
electronic health record
machine learning
big data
artificial intelligence