Efficacy and safety of chemotherapy in young patients with advanced gastroesophageal adenocarcinoma: data from the Spanish AGAMENON-SEOM registry.
Pablo Pérez-WertAna CustodioPaula Jimenez-FonsecaAlberto Carmona-BayonasArturo LecumberriDiego Cacho LavinItsaso Losantos GarcíaAna Fernández MontesJuana María CanoMaría Luisa LimónRaquel Hernández San GilMarc DiezRosario Vidal TocinoIsmael Macías DeclaraLaura VisaPaola Pimentel CáceresMireia Gil RagaElia Martínez MorenoTamara SauriMarta Martín RichardMónica GranjaPaula CerdàLucía Gómez GonzálezAntonio Mérida-GarcíaMaribel Ruiz MartínJavier Gallegonull nullPublished in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2023)
In the AGAMENON-SEOM registry, younger patients with GCYA exhibited more aggressive clinicopathological features, and despite receiving more aggressive treatments, similar efficacy outcomes and toxicity profiles were achieved compared to their older counterparts. In the AGAMENON-SEOM registry, GEAC in < 45 years showed more aggressive clinicopathological features and, although treated with more intense first-line CT regimens, similar efficacy outcomes and toxicity were achieved compared to older patients.