Genome-wide MNase hypersensitivity assay unveils distinct classes of open chromatin associated with H3K27me3 and DNA methylation in Arabidopsis thaliana.

Hainan ZhaoWenli ZhangTao ZhangYuan LinYaodong HuChao FangJiming Jiang

Published in: Genome biology (2020)

MNase can be used to identify open chromatin regions that are not accessible to DNase I or Tn5. Thus, MH-seq provides an important tool to identify and catalog all classes of open chromatin in plants.

Keyphrases

genome wide
dna methylation
arabidopsis thaliana
minimally invasive
gene expression
copy number
dna damage
transcription factor
high throughput
drug induced
oxidative stress
single cell