Investigating the Bidirectional Association of Rheumatoid Arthritis and Thyroid Function: A Methodologic Assessment of Mendelian Randomization.

Yuxuan TanHuojie YaoChuhang LinZhengtian LaiHaiying LiJing ZhangYingyin FuXiaomei WuGuang YangLiping FengChun Xia Jing

Published in: Arthritis care & research (2024)

Our results illustrate the significant bidirectional causal effect of RA and AITD, which holds even in multiple competing risk factors. Clinical screening for thyroid dysfunction in patients with RA deserves further attention, and vice versa.

Keyphrases

rheumatoid arthritis
disease activity
risk factors
ankylosing spondylitis
interstitial lung disease
working memory
systemic lupus erythematosus
oxidative stress
systemic sclerosis
idiopathic pulmonary fibrosis