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Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression.

Fabrizia BonacinaElisa MartiniMonika SveclaJasmine NourMarco CremonesiGiangiacomo BerettaAnnalisa MoregolaFabio PellegattaVeronica ZampoleriAlberico Luigi CatapanoMarinos KallikourdisGiuseppe Danilo Norata
Published in: Cardiovascular research (2022)
ACT with vasculotropic Tregs appears as a promising strategy to selectively target immune activation in the atherosclerotic plaque.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • cell therapy
  • cardiovascular disease
  • coronary artery disease
  • transcription factor
  • endoplasmic reticulum stress
  • type diabetes
  • oxidative stress
  • signaling pathway