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Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.

Haizhou WangYabo ZhouYangyang ZhangShilin FangMeng ZhangHaiou LiFei XuLan LiuJing LiuQiu ZhaoFan Wang
Published in: Journal for immunotherapy of cancer (2022)
Our study reveals that pMMR/MSS CRC is immunogenically heterogeneous and that GBP2 is a promising target for combinatorial therapy with ICB.
Keyphrases
  • binding protein
  • stem cells
  • human health
  • mesenchymal stem cells
  • bone marrow
  • climate change