Development of a candidate reference measurement procedure by ID-LC-MS/MS for total tau protein measurement in cerebrospinal fluid (CSF).
Chiara GiangrandeHélène VaneeckhoutteAmandine BoeufBéatrice LalereChristophe HirtzSylvain LehmannMilena QuagliaVincent DelatourPublished in: Clinical chemistry and laboratory medicine (2023)
The candidate RMP will pave the road towards global standardization of CSF t-tau measurements. Together with commutable Certified Reference Materials (CRMs), it will allow evaluating and improving the accuracy and comparability of results provided by IAs.