Clinical presentation and outcomes of non-typhoidal Salmonella infections in patients with cancer.
Nobuyoshi MoriAriel D SzvalbJavier A AdachiJeffrey J TarrandVictor E MulanovichPublished in: BMC infectious diseases (2021)
NTS affects predominantly patients with hematologic malignancies, followed by gastrointestinal and genitourinary cancers. Invasive disease, sepsis, and septic shock are common presentations among admitted patients. Antimicrobial prophylaxis may not prevent NTS infection. Thirty-day mortality and attributable mortality rates were low in our series compared to older case series. Early appropriate antibiotic therapy may have had a role in decreasing mortality. Relapses occurred in patients receiving ≤ 10 days of therapy, suggesting the need for longer duration of antibiotic therapy in cancer patients with uncomplicated NTS infections.
Keyphrases
- septic shock
- cardiovascular events
- end stage renal disease
- risk factors
- chronic kidney disease
- physical activity
- ejection fraction
- peritoneal dialysis
- intensive care unit
- stem cells
- type diabetes
- acute kidney injury
- staphylococcus aureus
- squamous cell carcinoma
- prognostic factors
- metabolic syndrome
- papillary thyroid
- coronary artery disease
- cardiovascular disease
- african american
- bone marrow
- insulin resistance
- lymph node metastasis
- childhood cancer