An antibody-free LC-MS/MS method for the quantification of sex hormone binding globulin in human serum and plasma.
Bas SleumerJordan ZwerwerMartijn van FaassenMichel J VosRainer BischoffIdo P KemaNico C van de MerbelPublished in: Clinical chemistry and laboratory medicine (2023)
The LC-MS/MS method which includes an albumin depletion step allows quantification of SHBG in serum and plasma without an immunocapture step at clinically relevant SHBG levels, thus contributing to better lab-to-lab consistency of results.