Identification of genetic variation in the swine toll-like receptors and development of a porcine TLR genotyping array.

Alex ClopAbe HuismanPieter van AsAbdoallah SharafSophia DerdakArmand Sanchez

Published in: Genetics, selection, evolution : GSE (2016)

We identified genetic variations that potentially have an impact on the protein sequence of porcine TLR. A genotyping array with 80 non-synonymous, 10 synonymous and three 3'UTR polymorphisms in the 10 TLR genes is now available for association studies in swine populations with measures on immune-related traits.

Keyphrases

genome wide
toll like receptor
high throughput
inflammatory response
immune response
dna methylation
nuclear factor
high resolution
genetic diversity
copy number
bioinformatics analysis
amino acid
single cell
high density
mass spectrometry
gene expression
small molecule
genome wide analysis