Dysregulation of Gut Microbiota-Derived Neuromodulatory Amino Acid Metabolism in Human Immunodeficiency Virus-Associated Neurocognitive Disorder: An Integrative Metagenomic and Metabolomic Analysis.

Xue ChenJiaqi WeiZhen LiYang ZhangXin ZhangLing ZhangXia WangYulin ZhangTong Zhang

Published in: Annals of neurology (2024)

Our findings provide new insights into the intricate interplay between the gut and microbiome-brain axis in the pathogenesis of HAND, highlighting the potential for developing novel therapeutic strategies that specifically target the gut microbiota. ANN NEUROL 2024.

Keyphrases

human immunodeficiency virus
hepatitis c virus
amino acid
antiretroviral therapy
hiv infected
white matter
hiv aids
hiv positive
resting state
multiple sclerosis
neural network
climate change
wastewater treatment
men who have sex with men
subarachnoid hemorrhage