The effects of Abemaciclib on cell cycle and apoptosis regulation in anaplastic thyroid cancer cells.

Elaheh S AbutorabiArash PoursheikhaniBahareh KashaniSahar ShamsaiegahkaniVahid HaghpanahDavood BashashSeied A MousaviMajid MomenySeyed H Ghaffari

Published in: Molecular biology reports (2023)

Our preclinical data highlight CDK4/6 as interesting therapeutic targets in ATC and suggest CDK4/6-blockade therapies as promising strategies in this malignancy.

Keyphrases

cell cycle
cell proliferation
oxidative stress
endoplasmic reticulum stress
cell cycle arrest
electronic health record
cell death
cell therapy
stem cells
data analysis