Deficit Accumulation Frailty Trajectories of Older Breast Cancer Survivors and Non-Cancer Controls: The Thinking and Living With Cancer Study.
Jeanne S MandelblattXingtao ZhouBrent J SmallJaeil AhnWanting ZhaiTim AhlesMartine ExtermannDeena GrahamPaul B JacobsenHeather JimBrenna C McDonaldSunita J PatelJames C RootAndrew J SaykinHarvey Jay CohenJudith E CarrollPublished in: Journal of the National Cancer Institute (2022)
Most survivors and controls remained robust, and there were similar proportions on a frail trajectory. However, there were differences in deficit patterns between survivors and controls. Survivor deficit accumulation trajectory was associated with patient-reported outcomes. Additional research is needed to understand how breast cancer and its treatments affect deficit accumulation.