The Ethanol Extract of Marine Sponge Aaptos suberitoides Suppress Cell Viability, Cell Proliferation and Cell Migration in HER2-Positive Breast Cancer Cell Line.

Muhammad Hasan BashariFadli Zaky ArsydinilhudaRe Septian IlhamsyahAnnisa Dewi NugrahaniRyzkianty Annis NurdinAjeng KartikaFathul HudaMaman AbdurahmanTenny PutriNurul QomarillaHarold AtmajaIkhwan Resmala SudjiBeginer SubhanHermin Aminah UsmanYunisa PamelaEko Fuji AriyantoEdy Meiyanto

Published in: Asian Pacific journal of cancer prevention : APJCP (2021)

This study revealed that the ethanol extract of Aaptos suberitoides demonstrates cytotoxicity, anti-proliferation and anti-migration effect as well as inhibition effect on three-dimensional spheroid growth in trastuzumab-resistant HER2+ breast cancer cell line.<br />.

Keyphrases

cell migration
positive breast cancer
cell proliferation
oxidative stress
signaling pathway
young adults
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