Whole-brain mapping of mouse CSF flow via HEAP-METRIC phase-contrast MRI.

Juchen LiMengchao PeiBinshi BoXinxin ZhaoJing CangFang FangZhifeng Liang

Published in: Magnetic resonance in medicine (2022)

We developed and validated a generalized HEAP-METRIC PC-MRI for mapping low velocity flow. With this method, we have achieved the first whole-brain mapping of awake mouse CSF flow and have further revealed that anesthesia reduces CSF flow velocity.

Keyphrases

high resolution
contrast enhanced
magnetic resonance imaging
high density
white matter
magnetic resonance
blood flow
computed tomography
diffusion weighted imaging
single cell
cerebral ischemia
multiple sclerosis