Validity and sensitivity to change of laser Doppler imaging as a novel objective outcome measure for cutaneous lupus erythematosus.

Md Yuzaiful Md YusofJ BrittonS EdwardE M A HensorM J GoodfieldP M LawsP EmeryM WittmannE M Vital

Published in: Lupus (2019)

LDI provides a reliable, valid and responsive quantitative measure of inflammation in CLE. It has a better correlation with histology compared to clinical instruments. LDI provides an objective outcome measure for clinical trials.

Keyphrases

clinical trial
high resolution
systemic lupus erythematosus
oxidative stress
disease activity
rheumatoid arthritis
blood flow
mass spectrometry
phase ii