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The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip.

Ali Alirezaie AlavijehMohammad BaratiMeisam BaratiHussein Abbasi Dehkordi
Published in: Advanced pharmaceutical bulletin (2019)
Cancer is an abnormal cell growth which tends to proliferate in an uncontrolled way and, in some cases, leads to metastasis. If cancer is left untreated, it can immediately cause death. The use of magnetic nanoparticles (MNPs) as a drug delivery system will enable drugs to target tissues and cell types precisely. This study describes usual strategies and consideration for the synthesis of MNPs and incorporates payload drug on MNPs. They have advantages such as visual targeting and delivering which will be discussed in this review. In addition, we considered body magnetic field to make drug delivery process more effective and safer by the application of MNPs and tumor-on-chip.
Keyphrases
  • magnetic nanoparticles
  • papillary thyroid
  • drug delivery
  • squamous cell
  • lymph node metastasis
  • cancer therapy
  • single cell
  • circulating tumor cells
  • squamous cell carcinoma
  • bone marrow
  • risk assessment