Thirty days after anterior cruciate ligament transection is sufficient to induce signs of knee osteoarthritis in rats: pain, functional impairment, and synovial inflammation.
Germanna de Medeiros BarbosaJonathan E CunhaThiago L RussoThiago M CunhaPaula A T S CastroFrancisco F B OliveiraFernando Q CunhaFernando S RamalhoTania F SalviniPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)
Our data showed that 30 days after ACLT is sufficient to induce signs of KOA in rats, such as pain, functional impairment, and synovial inflammation, suggesting that a shorter time period can be used as an experimental model.