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Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy.

Aksel LaudonZhaoze WangAnqi ZouRicha SharmaJiayi JiConnor KimYingzhe QianQin YeHui ChenJoel M HendersonChao ZhangVijaya B KolachalamaWeining Lu
Published in: bioRxiv : the preprint server for biology (2024)
We leveraged U-Net architecture in an algorithm to measure the widths of glomerular basement membrane and podocyte foot processes.Deep learning-based automated measurement of glomerular filtration barrier morphology has promise in podocytopathy research and diagnosis.
Keyphrases
  • deep learning
  • diabetic nephropathy
  • high glucose
  • machine learning
  • endothelial cells
  • artificial intelligence
  • convolutional neural network
  • big data
  • high throughput
  • neural network
  • single cell