Epilepsy in adult patients with tuberous sclerosis complex.
Aglaia VignoliFrancesca La BriolaKatherine TurnerAngela PeronChiara VannicolaValentina ChiesaElena ZambrelliFabio BruschiIlaria ViganòMaria Paola CaneviniPublished in: Acta neurologica Scandinavica (2021)
Epilepsy in TSC can be a lifelong disorder, but one-third of individuals reach seizure freedom by early adulthood. In the long term, age at epilepsy onset has a crucial role in drug resistance and in developing intellectual disability, both in drug-resistant and drug-sensible patients. Patients with drug-refractory seizures tend to develop psychiatric issues, which should be recognized and adequately treated.
Keyphrases
- drug resistant
- intellectual disability
- temporal lobe epilepsy
- end stage renal disease
- multidrug resistant
- autism spectrum disorder
- newly diagnosed
- acinetobacter baumannii
- chronic kidney disease
- ejection fraction
- mental health
- peritoneal dialysis
- depressive symptoms
- prognostic factors
- emergency department
- adverse drug
- pseudomonas aeruginosa
- drug induced